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技術(shù)文章您現(xiàn)在的位置：首頁 > 技術(shù)文章 > Kdo Azide點擊化學革蘭氏陰性菌標記ClickChemistryTools特色產(chǎn)品

Kdo Azide點擊化學革蘭氏陰性菌標記ClickChemistryTools特色產(chǎn)品

更新時間：2023-08-11   點擊次數(shù)：1024次

產(chǎn)品描述：

Kdo-Azide,疊氮標記代謝物，是一種含疊氮化物的代謝蛋白標記試劑可以納入唾液酸的生物合成途徑。疊氮化改性蛋白檢測用熒光或生物素炔炔烴。3-脫氧-D-甘露寡糖酸（Kdo）的一種含疊氮化物的類似物。8-疊氮基-3,8-二脫氧-D-二十二碳五烯酸（Kdo-Azide）是天然3-脫氧-D-二十碳五烯酸的類似物，其含有非常小的修飾，特別是疊氮基部分。這種分子可以被培養(yǎng)的細胞（例如革蘭氏陰性菌）摻入，并在活性聚糖生物合成過程中摻入聚糖（例如LPS）。檢測利用疊氮化物與炔烴或環(huán)辛烯之間的化學選擇性連接或“點擊"反應。

8-Azido-3,8-dideoxy-D-manno-octulosonic acid (Kdo Azide) is an analogue of the natural 3-deoxy-D-manno-octulosonic acid (Kdo) that contains a very small modification, specifically an azido moiety. This molecule can be incorporated by cultured cells (Gram-negative Bacteria, for example) and incorporated into glycans (LPS, for example) during active glycan biosynthesis. Detection utilizes the chemoselective ligation or “click" reaction between an azide and an alkyne or cyclooctyne.

Kdo Azide cas：1380099-68-2 疊氮化物點擊化學試劑

英文名稱：Kdo-Azide,Kdo-N3

中文名稱：3-去氧-D-甘露-2-辛酮糖酸疊氮糖

英文同義詞：Kdo-Azide,Kdo-N3

Kdo Azide

Kdo-N3

Kdo azide(NH3)

結(jié)構(gòu)：

59ef79c6a3481d86aec718eaf027aa8d_1241_Structure.png

分子式：C8H16N4O7

分子量：280.24

cas:1380099-68-2

image.png


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靶點科技（北京）有限公司

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