上司的妻子免费观看正版电视剧,欲妇荡岳丰满少妇岳,中文字幕一区二区三区乱码,人人妻人人澡人人爽欧美精品,性一欲一乱一仑,小说都有什么类型,演过三级的韩国女星,万相之王起点小说网,www韩国三级电影,少妇又黄又湿又色的视频在线免费观看

技術(shù)文章您現(xiàn)在的位置:首頁 > 技術(shù)文章 > BroadPharm藥物遞送中的脂質(zhì)Lipids In Drug Delivery選購指南

BroadPharm藥物遞送中的脂質(zhì)Lipids In Drug Delivery選購指南

更新時間:2024-12-06   點(diǎn)擊次數(shù):780次

脂質(zhì)是一類有機(jī)分子,是脂肪酸或其衍生物。脂質(zhì)不溶于水,但溶于有機(jī)溶劑。

脂質(zhì)廣泛用于化妝品和食品工業(yè),脂質(zhì)分子也已成功用于納米顆粒形成和 mRNA 核酸遞送,這導(dǎo)致了兩種疫苗 mRNA-1273 和 BNT162 以及其他臨床批準(zhǔn)藥物的成功。

BroadPharm 提供各種先進(jìn)的脂質(zhì)分子,如可電離脂質(zhì)、陽離子脂質(zhì)、磷脂、PEG 脂質(zhì)、膽固醇等。對我們?nèi)虻目蛻?。我們還

提供新型脂質(zhì)分子的快速定制合成,以增強(qiáng)您在制藥和生物技術(shù)領(lǐng)域的高級研究能力。國內(nèi)客戶可以連續(xù)授權(quán)代理商靶點(diǎn)科技。


Lipids are a class of organic molecules that are fatty acids or their derivatives. Lipids are insoluble in water but soluble in organic solvents.

Lipids are widely used in the cosmetic and food industries, Lipid molecules have also been successfully used in nanoparticle formation and mRNA nucleic acid delivery, which lead to the success of the two  vaccines, mRNA-1273 and BNT162 and other clinical approved drugs.

BroadPharm offers a wide array of advanced lipid molecules, such as ionizable lipids, cationic lipids, Phospholipid, PEG lipids, Cholesterol.. to our clients worldwide. We also provide fast- speed custom synthesis of novel lipid molecules to empower your advanced research in the pharmaceutical & biotech field.

BroadPharm藥物遞送中的脂質(zhì)Lipids In Drug Delivery選購指南



脂質(zhì)體(Liposome):納米顆粒的一種亞型,由疏水尾部和親水頭部構(gòu)成磷脂膜。

微球(Microspheres):蛋白質(zhì)或合成聚合物組成,在性質(zhì)上是可生物降解的,理想的粒度在1-1000μm。

膠束(Micelles):由兩親性聚合物自聚集形成的。

微晶(Nanocrystals):改變晶體大小,從而改變藥物體內(nèi)行為。

原位凝膠(Insitugel):進(jìn)入人體之前以溶液形式存在的制劑,但在各種生理?xiàng)l件下會轉(zhuǎn)變?yōu)槟z形式。



靶點(diǎn)科技(北京)有限公司

靶點(diǎn)科技(北京)有限公司

地址:中關(guān)村生命科學(xué)園北清創(chuàng)意園2-4樓2層

© 2025 版權(quán)所有:靶點(diǎn)科技(北京)有限公司  備案號:京ICP備18027329號-2  總訪問量:339806  站點(diǎn)地圖  技術(shù)支持:化工儀器網(wǎng)  管理登陸

{????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}| {????′ê}|